I. GROSS ANATOMY: Learn to recognize and identify the
following structures on plastic models, torsos
and preserved specimen available in the
lab.
A. Pituitary gland in sella turcica
B. Pineal gland; hormone: melatonin
C. Thyroid gland
D.
Parathyroid glands; hormone: parathyroid hormone (PTH)
E. Pancreas
F. Adrenal glands
G. Ovaries and Testes
II. HISTOLOGY: Learn to recognize and
identify the following structures in microscopic view, and give a
function or product where applicable
A.
Pituitary gland (hypophysis)
1. Anterior lobe (adenohypophysis): cells appear dense, cytoplasm staining
darkly
a. Gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
b. Adrenocorticotropic hormone (ACTH)
c. Thyroid-Stimulating Hormone (TSH)
d.
Growth Hormone (GH)
e. Prolactin (PRL)
2. Posterior
lobe (neurohypophysis): cells are few, overall appearance is fibrous,
lightly
stained
a. Oxytocin
b. Antidiuretic hormone (ADH)
B. Thyroid gland: follicles containing thyroglobulin (aka colloid)
1. Thyroid hormone: T4 (thyroxine) and T3
(triiodothyronine)
2. Calcitonin (aka thyrocalcitonin)
C. Pancreas
1. Acini--darkly stained pyramid-shaped cells arranged 5-8 cells with tip of
pyramid
pointing
toward central duct, base of pyramid to outside; this is the exocrine
portion of
the
pancreas.
2. Islets--isolated
clusters of cells; cytoplasm doesn't stain well, nuclei stand out; this is
the
endocrine portion of the pancreas.
a. Insulin
b. Glucagon
D. Adrenal gland: Look at the slide first without the
microscope by holding it up to the light
or
by placing the slide on a white
sheet of paper. Notice a difference in color shading
between
the outer rim and an inner
strip of tissue. The outer rim is the cortex. The inner strip is
the
medulla. Place the slide
on the scanning lens and re-examine for the cortex and
medulla.
1. Cortex
a. Mineralocorticoids (aldosterone)
b. Glucocorticoids
c.
Gonadocorticoids (sex hormones)
2. Medulla
a. Epinephrine
b. Norepinephrine
E. Ovary
1. Primordial follicles
at or near outer surface of ovary
2.
Primary follicles containing primary oocytes surrounded by cuboidal cells
3.
Secondary follicles containing secondary oocyte and first sign of antrum
4.
Graafian (or vesicular) follicle
5. "Ovum"
with corona radiata and zona pellucida
6. Hormones
a. Estrogen
b. Progesterone
c. Inhibin
d. Relaxin
F. Testes
1.
Seminiferous
tubules (cross-section): round or oval structures with lumen
2.
Germinal epithelium with spermatogonia at periphery of seminiferous
tubules
3. Interstitial
cells
4. Spermatids near or in
lumen
5. Hormones
a. Testosterone
b. Inhibin
FOR THE LAB PRACTICAL, BE ABLE TO RECOGNIZE ANY OF THE ABOVE ENDOCRINE GLANDS AND STRUCTURES ASSOCIATED WITH THEM, EITHER IN GROSS PRESENTATION OR MICROSCOPIC PRESENTATION. BE ABLE TO NAME A PRODUCT OF A PARTICULAR PART OF A GLAND OR A FUNCTION OF A PARTICULAR STRUCTURE IN THE GLAND.